When a college girl at a Catholic university commits suicide, Gus and Shawn are brought in because one of the professors at the school believes the girl was demon-possessed.

When Martha comes down with a strange disease, Professor Fine convinces Clark that Jor-El is responsible and that the Fortress must be trying to eliminate the father of Kal-El. But…

Sam and Dean come to the aid of Sam’s old college buddy after he is accused of a murder he swears he didn’t commit. The brothers discover a shapeshifter is…