The citizens of Defiance prepare to cast their votes for mayor; Nolan’s past violently rears its head; Irisa must decide whether or not to embrace her destiny.

Amanda’s mayoral campaign is threatened when Nolan is involved in an accident on the eve of the election, prompting the town to question Amanda’s decision to appoint him as Lawkeeper.

A deadly plague threatens the town; racial tensions rise when the Irathients, who are immune to the virus, are quarantined.

Eph and Nora fight to save Captain Redfern’s life before coming face-to-face with the horrifying effects of the virus. A spike in rat attacks signals Fet that something inexplicable is…