Sully ends up badly beaten and partially paralyzed following a run in with buffalo hunters who were hired by the railroad to clear the buffalo and Indians out of the…

Dr. Mike takes in Red McCall, a down-and-out cowboy, and his ailing half-breed infant child. McCall reaches the end of his rope trying to care for his baby, so after…

Dr. Mike tries to heal the soul of Doc Eli, a Civil War surgeon turned patent medicine show huckster, who’s come to like the taste of his own medicine, an…

When several townspeople come down with mercury poisoning, Dr. Mike forces a reluctant Sully to guide her to the high mountain stream which may be the source of the problem….

As Dr. Quinn is trying to persuade the townspeople that smallpox vaccinations are necessary, the father of Brain, Colleen, and Matthew arrives.

A bitter Loren, who blames Sully for his daughter’s death, tries to repossess Dr. Mike’s cabin when he learns he still owns the deed.

A gunslinger (Johnny Cash) arrives looking for a quiet town in which to hang ’em up, but Colorado Springs is itching to lynch an immigrant (Christopher Keene Kelly) for cattle…

Mike’s estranged mother (Jane Wyman) visits, but she and Mike are still miles apart. Meanwhile, Robert E is injured in a fire.

Horror mounts when a flu epidemic attacks Colorado Springs. Dr. Mike must attend the sick townspeople and protect others from getting the deadly disease. But being a lady doctor has…

Michaela “Mike” Quinn, of Boston, followed in her father’s footsteps by becoming a doctor. Dr. Mike worked side by side her father. But his sudden death caused her the loss…

A female Ferengi, posing as a male to be available to participate in business (a rule STRICTLY forbidden by the Ferengi government), falls for Quark during very important negotiations between…