Eph and Nora fight to save Captain Redfern’s life before coming face-to-face with the horrifying effects of the virus. A spike in rat attacks signals Fet that something inexplicable is…

The four survivors begin manifesting strange symptoms, but Eph and Nora’s attempt to quarantine them is thwarted as the disinformation campaign begins. Meanwhile, in jail, Setrakian receives a surprise visit…

When a plane lands in New York City with everyone on board dead, Dr. Ephraim Goodweather, head of the CDC’s Canary Project, and his team are called upon to investigate….

The romance between Inspector Murdoch and Dr. Ogden heats up as Murdoch finds himself investigating the death of a young woman working as a high-class prostitute.

Sam and Dean investigate a case where people are suffering violent deaths after hearing a mysterious song.

Sam, Dean, and Bobby hunt down Lilith and fight her and her demons in a final effort to save Dean’s life.