The citizens of Defiance prepare to cast their votes for mayor; Nolan’s past violently rears its head; Irisa must decide whether or not to embrace her destiny.

Amanda’s mayoral campaign is threatened when Nolan is involved in an accident on the eve of the election, prompting the town to question Amanda’s decision to appoint him as Lawkeeper.

A deadly plague threatens the town; racial tensions rise when the Irathients, who are immune to the virus, are quarantined.

Kenya is kidnapped. Rafe learns that Luke was involved in some mysterious goings-on at the mines and orders Quentin to get to the bottom of it.