Supergirl and the team go head to head against Rama Khan and Leviathan. Meanwhile, Lena and Lex must join forces when Project Non Nocere fails, leaving the two siblings in…

Supergirl realizes that in order to stop Lex and Leviathan she must work with the one person she never thought she’d trust again – Lena. Nia keeps dreaming about Brainy…

Addison flirts with a colleague at St. Ambrose Hospital; Sheldon and Pete try to convince Violet to take a paternity test; Sam accidentally calls Sonya by the wrong name.

Addison suspects that Archer is up to his old tricks; a patient’s child is born with male and female reproductive organs; Violet and Sheldon co-lead a therapy group for couples.

Addison’s brother, Archer, moves to Los Angeles to work at Pacific Wellcare; Cooper encourages Violet to discuss her pregnancy with Pete and Sheldon.

Nick and Hank are called to the scene of a gang-related homicide. The case escalates as Zuri, Hank’s physical therapist, and her brother get caught up in the investigation. Meanwhile,…

Nick and Hank investigate a Wesen “healer” whose ability holds risks that far outweigh its rewards. Meanwhile, Juliette takes in a friend when domestic issues escalate and Hank makes a…

Nick leans on Monroe and Rosalee as he worries that he may lose everything as he continues to battle Black Claw. Renard ramps up his campaign as election time nears….

Suffering from the bite he sustained, Sargeant Wu becomes entangled in a surprising altercation that may land him in hot water. After meeting the mysterious Bonaparte, Adalind is faced with…

Eliza throws Alex and Maggie a wedding shower, which causes Maggie to reach out to her estranged father. Supergirl joins J’onn on a personal mission.

Psi, a thief with psychic powers, attacks National City. Able to immobilize people by tapping into their worst fears, Psi proves a formidable opponent for Supergirl. Meanwhile, James and Lena…

Supergirl challenges Rhea to battle to save National City. Meanwhile, Superman returns and Cat Grant offers Supergirl some sage advice.

Armek, a White Martian, descends on National City intent on taking M’gann back to Mars to face her punishment as a traitor. Hank and Supergirl determine the best way to…

After Livewire seemingly breaks out of prison, Supergirl is intent on recapturing her. After training Mon-El, Supergirl takes him with her when she sees Livewire attack the NCPD but things…

While Guardian tries to clear his name after being accused of a murder committed by another vigilante, Supergirl heads out on a solo mission to rescue Mon-El who has been…

The Guardian debuts to lend a hand after a parasite alien drains Supergirl of her power. Mon-El considers a less than desirable new career which then leads him to contemplate…

When Kara and Alex investigate the murder of an unregistered alien, the trail leads to an alien fight club run by Roulette, the ringmaster who commands aliens to fight in…

An attack is made on the President as hot-button, alien vs. human rights issues heat up in National City. Supergirl and the DEO are assigned to protect the President and…

Harvey and Jessica’s relationship is tested when Harvey defends someone from her past. Also, Louis assigns Mike his first solo case, a pro bono that has him itching for a…

In the aftermath of the quarantine, the staff tries to return to their normal routines. Meanwhile, as Dr. Lim recovers from the virus, she and Dr. Melendez navigate their new…

Dr. Claire Brown faces complications at home and work as she prepares to lead her first surgery. Meanwhile, a sports fishing accident challenges the rest of the staff as they…

As Dr. Marcus Andrews vows to help a good Samaritan who was injured while stopping a sexual assault, Dr. Audrey Lim faces a difficult decision when a young patient’s parents…

When the team treats a patient who has to decide between a dangerous surgery that could change his life or remain the same, he asks Dr. Shaun Murphy what he…